TL;DR: You will routinely play this for 3 or 4 icons and be happy for it.

Don't underestimate this beute. Depending on your investigator, having just 2-3 cards in your hand isn't an unlikely scenario. If this is one of three cards in your hand when played, that means you're getting 3 icons. One of two cards, 4 icons. Last card, 5 icons.

3 icons is by no means bad for a skill card, if a 3 icon "Play only if you have 2 or less other cards in your hand" existed, people would play it. This is that card, and then some.

4 Icons for one card is terrific, and definitely and achievable play once or twice in a scenario.

5 Icons is the golden-egg-laying goose that you think you're picking this card for, but believe me, this is not going to happen a lot.

Wendy and Ashcan, with their card discard mechanics are the obvious optimal character to use this card with, thanks to their innate discard abilities, on the other hand if Last Chance doesn't look playable they can discard it for their abilities.

So... this card reminds me very much of Preposterous Sketches, a card that is honestly pretty mediocre. The simple reality is that paying 2 resources and an action to draw three cards isn't economically viable in a game that is essentially about action management.

However, this card has one two major upsides over Sketches. The first one is that it cannot find weaknesses. This is actually a bigger deal than it seems at first glance since weaknesses are a major reason not to aggressively draw cards.

The second reason is the selection. You don't play backpack in any deck, you play it in a deck that has multiple Item or Supply cards that you really need. Here is a list of all Item and Supply cards.

While it could hit Emergency Cache (and is probably nice if it does hit at least one), you are really looking for decks that run a large number of qualifying cards. Mathematically, you want half your deck to be Item/Supply cards (probably more so you don't miss). Because that's the problem with this card: if you don't get three cards under it, it's really quite mediocre.

That being said, if you ever get Lightning Gun, Extra Ammunition and Emergency Cache on this thing... that's pretty good.

However, because it also takes up a body slot (not the most contested, but not trivial either), I don't see this card getting a ton of play. So, better than Sketches in a few decks, but probably still not the Diesel we need.

Innate cards, which are those? It's: Unexpected Courage, Guts, Manual Dexterity, Rise to the Occasion, "Not without a fight!", Resourceful and Survival Instinct. Out of faction there's Eureka!, Inquiring Mind, Opportunist, Quick Thinking, Fearless, Defiance and Inspiring Presence.

Some pretty good cards there, Resourceful in particular has big combo potential, you can recurse True Survivor with it and basicly play infinite skill cards.

To routinely hit 2+ cards with True Survivor you need 6+ of them in your deck, preferably as many as 8, that means that you're using Unexpected Courage, the most flexible of the bunch, Resourceful since it further enhances your recursion and its also flexible. The other 2-4 cards would depend on the exact survivor but generally all of them can put "Not without a fight!" to use. I wouldnt take "Not without a fight!" in a deck if you dont intend to get True Survivor.

This is a big nope In Wendy, perhaps the character where it would be the best. If you can stomach the risk of removing all your hard-earned skill cards when you draw her weakness then by all means try it. Mind you that it's not QUITE as bad as it might seem but just keep it in mind when you plan the deck.

Silas Bishop is going to love this card, it's probably going to be very good complement to his skill-heavy ability.

Dog and "Ashcan" Pete can do lots of stuff with True Survivor but perhaps most notably is the fact that he can recurse Inspiring Presence, a very nice combo interaction.

William Yorick can do a similar combo with Inspiring Presence, reloading upgraded Beat Cops for example.

UPDATE: After trying this card a bunch in Silas Marsh I can say that it's a terrific way to reload your hand, but the tempo is so terrible that having enough time and money to pay for just the one True Survivor is difficult enough. You want to draw and play this thing late in a game, when most of your cards are in the discard pile. If you really want this effect more then once then recurse it with Resourceful.

While this card benefits from having the ability to cancel any encounter card YOU draw, it loses out on utility to its level 2 younger brother by not being able to protect your fellow investigators. I'd rather have the ability to help out an investigator or even the whole party on a particularly treacherous drawn encounter than being able to discard an enemy. (which most Mystics shouldn't have a problem dealing with anyway with the right spells)

This card gets panned for good reason. It costs a lot for something that other cards already do at level 0. However, with the Vengeance mechanic in the Forgotten Age, it will be interesting to see if this card moves up in priority at all. It's one that I would keep an eye on for now, to see if it ever makes it into someone's deck.