This could be an interesting card for Trish (OG). She can keep enemies around to trigger her ability more safely and should then have no problem clearing locations and resealing tokens on Misdirection.
I'm quite curious about the following interaction with this card: Your investigator is engaged with an enemy and decides to investigate. You then cancel the attack of opportunity with Misdirection and move to a connecting location (the enemy comes with as it's engaged). You have now paid the cost of initiating the Investigate action. Which location do you investigate? The one you started at or the one you move to with Misdirection?